Which phase involves remodeling of tissue and maturation of collagen?

Which phase involves remodeling of tissue and maturation of collagen?

• A. Remodeling
• B. Proliferation
• C. Epithelization
• D. Hemostasis

Answer: (A)

Remodeling is the phase where tissue is reorganized and collagen matures. After the initial wound healing steps lay down collagen during proliferation, this stage realigns and strengthens the tissue by converting weaker type III collagen into stronger type I collagen, increasing tensile strength and shaping the scar along lines of tension. This process takes weeks to months and results in a progressively stronger, less prominent scar as remodeling continues. Proliferation focuses on forming granulation tissue and epithelial coverage, while hemostasis is the immediate clotting response, and epithelialization occurs during that early proliferative period.

Remodeling is the phase where tissue is reorganized and collagen matures. After the initial wound healing steps lay down collagen during proliferation, this stage realigns and strengthens the tissue by converting weaker type III collagen into stronger type I collagen, increasing tensile strength and shaping the scar along lines of tension. This process takes weeks to months and results in a progressively stronger, less prominent scar as remodeling continues. Proliferation focuses on forming granulation tissue and epithelial coverage, while hemostasis is the immediate clotting response, and epithelialization occurs during that early proliferative period.