What is the main event during epithelization?

What is the main event during epithelization?

• A. An initial barrier of tissue is forming
• B. WBC influx peaks
• C. Fibroblasts invade wound
• D. Blood clot forms

Answer: (A)

Re-epithelialization is the restoration of the skin’s barrier, carried out by keratinocytes at the wound edges migrating across the wound bed and forming a new epithelial layer. This newly formed epithelial barrier is the defining event of this phase, reestablishing a protective surface and helping prevent infection. Other events belong to earlier or later wound-healing processes—blood clot formation happens in hemostasis, WBC influx peaks during inflammation, and fibroblasts invade to create granulation tissue and lay down ECM during the proliferative phase.

Re-epithelialization is the restoration of the skin’s barrier, carried out by keratinocytes at the wound edges migrating across the wound bed and forming a new epithelial layer. This newly formed epithelial barrier is the defining event of this phase, reestablishing a protective surface and helping prevent infection. Other events belong to earlier or later wound-healing processes—blood clot formation happens in hemostasis, WBC influx peaks during inflammation, and fibroblasts invade to create granulation tissue and lay down ECM during the proliferative phase.