Negative feedback in neurons is defined as

Negative feedback in neurons is defined as

• A. Negative feedback
• B. Positive feedback
• C. Facilitation
• D. Inhibition

Answer: (A)

Negative feedback is a regulatory mechanism that counters a deviation from baseline by producing effects that oppose the original stimulus. In neurons, when activity or signal strength rises, systems activate to dampen the response and bring activity back toward the baseline. This is what defines negative feedback: the response acts to oppose the initial change. For example, an inhibitory interneuron can suppress the original neuron’s activity, or an autoreceptor can reduce neurotransmitter release, or calcium-activated potassium channels can hyperpolarize the cell to lower excitability. Positive feedback would amplify the change, facilitation refers to a temporary boost in synaptic strength with repeated stimulation, and inhibition describes reduced activity but not necessarily a self-l regulating loop that opposes the initial stimulus.

Negative feedback is a regulatory mechanism that counters a deviation from baseline by producing effects that oppose the original stimulus. In neurons, when activity or signal strength rises, systems activate to dampen the response and bring activity back toward the baseline. This is what defines negative feedback: the response acts to oppose the initial change. For example, an inhibitory interneuron can suppress the original neuron’s activity, or an autoreceptor can reduce neurotransmitter release, or calcium-activated potassium channels can hyperpolarize the cell to lower excitability. Positive feedback would amplify the change, facilitation refers to a temporary boost in synaptic strength with repeated stimulation, and inhibition describes reduced activity but not necessarily a self-l regulating loop that opposes the initial stimulus.