In the orthopedic injury model, what event occurs directly after leukocytes engulf bacteria?

In the orthopedic injury model, what event occurs directly after leukocytes engulf bacteria?

• A. Leukocytes join phagosome to form phagolysosome
• B. Leukocytes approach bacteria
• C. Leukocytes digest bacteria
• D. Bacteria replicate rapidly

Answer: (A)

After leukocytes engulf bacteria, the immediate next event is the fusion of the phagosome with a lysosome to form a phagolysosome. This fusion creates a digestive environment loaded with lysosomal enzymes and reactive oxygen species that digest and kill the bacteria. Approaching bacteria happens before engulfment, and digestion occurs after phagolysosome formation, not directly at engulfment, while bacteria replication isn’t part of this sequence. In orthopedic injury, efficient phagolysosome formation helps clear bacteria and debris, aiding healing.

After leukocytes engulf bacteria, the immediate next event is the fusion of the phagosome with a lysosome to form a phagolysosome. This fusion creates a digestive environment loaded with lysosomal enzymes and reactive oxygen species that digest and kill the bacteria. Approaching bacteria happens before engulfment, and digestion occurs after phagolysosome formation, not directly at engulfment, while bacteria replication isn’t part of this sequence. In orthopedic injury, efficient phagolysosome formation helps clear bacteria and debris, aiding healing.